How multiple sclerosis affects the body's nerves E-mail
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Multiple Sclerosis Questions and Answers

Multiple Sclerosis is a demyelinating disease. This means that it attacks the myelin coating around the nerves and axons. The myelin is an insulating substance that allows nervous signals to travel fast to their destination. When the demylination occurs, there are several symptoms that the sufferer experiences, which are not pleasant at all.


The symptoms are:

Fatigue – MS sufferers are affected by normal fatigue, and MS specific fatigue, called lassitude – a feeling of constant sleepiness, besides neuromuscular fatigue.

Spasticity - which is the result of the dysfunction of an upper motor neuron that controls impulse and neurochemistry.

Weakness – appears because of the demyelination, and deconditioning; however, the muscles are only neurologically weakened.

Urinary dysfunction – the symptoms can include incontinence, hesitancy, frequency, urgency, et cetera.

Bowel dysfunction – most commonly constipation

Sexual dysfunction - impotence in men and decreased vaginal lubrication for women.

Pain – a very common symptom, which presents itself in various forms: irritative, burning, dysesthesia, et cetera.

Visual Dysfunction – which can mean loss of color,  blurry vision, phosphenes, and other

Paroxysmal spasms – meaning that the paroxysmal  electrical short-circuiting of the spinal cord, which leads to sensory disturbances and spasms.

Pathological laughing or crying – this occurs when MS demyelination affects the peudobulbar palsy.

Depression – again, the demyelination affects and changes the brain’s neurochemistry, and this leads to depression ( not that having MS it’s in itself depressing).

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