Multiple sclerosis is a progressive disease, which means that its symptoms are only going to worsen over time. However, the progression of the disease differs from person to person, so there is no saying if the decline will happen in a matter of years or decades.

Back to the original question, Multiple Sclerosis patients can expect:

Fatigue – MS sufferers are affected by normal fatigue, and MS specific fatigue, called lassitude – a feeling of constant sleepiness, besides neuromuscular fatigue.

Spasticity  - which is the result of the dysfunction of an upper motor neuron that controls impulse and neurochemistry.

Weakness – appears because of the demyelination, and deconditioning; however, the muscles are only neurologically weakened.

Urinary dysfunction – the symptoms can include incontinence, hesitancy, frequency, urgency, et cetera.

Bowel dysfunction – most commonly constipation

Sexual dysfunction - impotence in men and decreased vaginal lubrication for women.

Pain – a very common symptom, which presents itself in various forms: irritative, burning, dysesthesia, et cetera.

Visual Dysfunction – which can mean loss of color,  blurry vision, phosphenes, and other

Paroxysmal spasms – meaning that the paroxysmal  electrical short-circuiting of the spinal cord, which leads to sensory disturbances and spasms.